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New Approaches for Therapeutic Pulmonary RNA Delivery

18 July 2023

To meet the medical need of efficient RNA delivery beyond the liver, my lab rationally designs inhalable and biocompatible nanocarriers for efficient siRNA delivery to the lung. Delivery is the major hurdle thwarting the therapeutic potential of RNA medicines. While all siRNA drugs on the market target the liver, the lung offers a variety of currently undruggable targets which could be treated with RNA therapeutics. Hence, nebulizable and biocompatible nanocarriers for pulmonary administration of RNA nanoparticles could finally enable delivery beyond the liver. 

- Mathew Cherian PhD, Consultant Self Employed - The United States
- Nikolina Biskic, Global Regulatory Affairs Manager, Croatia

- Olivia Merkel, Professor Chair Drug Delivery, Ludwig Maximillian University (LMU), Munich - Germany